4-HO-MET Spray Bottles

4-Hydroxy-N-methyl-N-ethyltryptamine, commonly referred to as 4-HO-MET, is a synthetic compound belonging to the tryptamine class of chemicals. It is structurally related to psilocin, the active component in psilocybin mushrooms, and shares a core structure typical of tryptamines. The molecular formula of 4-HO-MET is C₁₃H₁₈N₂O, with a molecular weight of approximately 218.3 g/mol  . This compound was first synthesized by the American chemist Alexander Shulgin, who documented its effects in his book TiHKAL (Tryptamines I Have Known and Loved)

The psychedelic research results of 4-HO-MET are believed to stem from its activity on the 5-HT2A receptor as a partial agonist. However, this role and how they result in these research results remains the subject of ongoing scientific research. Opportunity for researchers to investigate this further!

How to use 4-HO-MET Spray Bottles?

Ensure to store the 4-HO-MET Spray Bottles in a dry and cool place for maximum shelf-life. When handling research chemicals ensure to always take the proper precautions in the laboratory like wiping down surfaces and wearing gloves, a mask & protective clothing. We strongly advised using harm reduction practices when using research chemicals.

Definition 4-HO-MET 

The definition of 4-HO-MET is officially known as 4-Hydroxy-N-methyl-N-ethyltryptamine.  Schleeb, colour, methylcybin, metocin are all common names that are used for this lesser-known psychedelic of the tryptamine class. 4-HO-MET is structurally related to psilocin also known as the magic mushroom.

Chemistry background information 4-HO-MET

4-HO-MET, or 4-hydroxy-N-ethyl-N-methyltryptamine, is a synthetic molecule of the tryptamine class. Tryptamines share a core structure consisting of a bicyclic indole heterocycle linked at R3 to an amino group via an ethyl side chain. 4-hydroxy-N-ethyl-N-methyltryptamine also contains a methyl group and an ethyl chain bonded to the terminal amine RN of its tryptamine backbone (MET).

4-HO-MET is related to 4-AcO-MET and psilocin (4-HO-DMT). It is also the 4-hydroxyl analog of the base tryptamine MET. The psychedelic outcomes are believed to derive from its activity on the 5-HT2A receptor as a partial agonist. However, the role of these outcomes and how they result remains the subject of ongoing scientific research.

Where to buy 4-HO-MET

4-HO-MET can be purchased here on the Realchems website. We sell premium quality 4-HO-MET, typically in pellets and spray form. However, we often have other substance forms available, so feel free to contact us to see if we have your preferred substance form in stock. You must be at least 18 years old to buy 4-HO-MET from us.